Cystic fibrosis in the crosshairs at iGEM

The iGEM (International Genetically Engineered Machine) synthetic biology competition will not be able to take place in person in Boston this year. Instead, teams will compete online and through videos. The Grenoble team, made up of four Grenoble Institute of Technology-Phelma students, is entering PyroBusters, its weapon against P.aeruginosa, a bacteria responsible for many secondary lung infections in patients suffering from cystic fibrosis and, more generally, for hospital-acquired infections.
PyroBusters will detect and destroy the biofilm (a community of microorganisms that adhere to surfaces like the respiratory tract) utilizing a novel drug delivery method. The team designed an automated test bench that reproduces the pulmonary environment’s temperature, moisture, and movement and that includes fluorescence imaging to visualize the treatment.

Contact: sebastien.rigollet@grenoble-inp.org

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