Lensless imaging could make phage therapy faster

Researchers from CEA-Leti, Irig, and LTM recently worked with a team in Lausanne* to develop a lensless device capable of reducing the time it takes to identify active phages on antibiotic-resistant bacteria at least threefold. The large-area image sensor (24×36 mm²) reads the optical signature of areas occupied by bacterial debris. The technique could be more effective than naked-eye observation and would result in fewer false negatives.

An ANR (France’s national research agency) priority program to develop the technique further is about to begin in conjunction with Hospices civils de Lyon, a major university medical center. According to the WHO, antibiotic-resistant infections could cause 10 million deaths per year by 2050, making phage therapy a strategic solution.

*Lausanne University Medical Center (CHUV) bacteriophage and phage therapy lab

Contact: camille.giroud@cea.fr

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